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College Basketball

LUC Loyola Chicago @ SLU Saint Louis -22.5

Wednesday, March 4, 2026 · Wed, March 4th at 8:00 PM EST
Pick
Under 156.5
🔥🔥🔥🔥
WIN Final: 65-79
Jump to analysis
Secondary Pick
Saint Louis -22.5
LOSS

The Revenge Game That Isn't Close

Saint Louis already hung 86 on Loyola Chicago three weeks ago in Chicago, winning by 27. Now they get them at home, where they're 19-1 and averaging more defensive intensity than the road. The market opened this at -22.5 and hasn't budged — that's respect for a 26-3 team that knows exactly how to attack a 7-22 opponent they've already dismantled.

Here's the angle: Loyola Chicago can't score in structured halfcourt sets, and Saint Louis forces exactly that style. The Ramblers average 74.5 PPG on the season, but in their last five road games they've hit 61, 59, 64, and 59 — only once over 65. Saint Louis plays at a glacial pace (62.7 PPG suggests they shorten possessions and grind), and when Loyola can't push tempo, they collapse. In the first meeting, Loyola managed just 59 points. On the road, where they're 2-9, they've been held under 65 in four of their last five.

The total opened at 156.5, and I'm seeing Under -112. Saint Louis has four days rest, which means they'll be sharp defensively, and Loyola's offensive ceiling on the road is around 62-65 points max. If Saint Louis scores their season average of 63 at home, we need Loyola to hit 94 for this to go Over. That's absurd. Even if the Billikens push into the mid-70s in a revenge beatdown, Loyola isn't cracking 70 in this building.

The secondary angle: Loyola is 2-9 on the road and just got embarrassed by 27 three weeks ago. There's no pride bounce here — they're 7-22 and playing out the string. Saint Louis is 26-3 and hunting a conference title. This is a mismatch of motivation, talent, and pace control.

Pick: Under 156.5 (-112)
Confidence: 4 units

Secondary Pick: Saint Louis -22.5 (-110)
Confidence: 2 units

Saint Louis covers by keeping this ugly. Loyola struggles to score in halfcourt sets, and the Billikens play that exact style. The spread is big, but it's justified — they won by 27 in Chicago, and home court only widens the gap.

LUC Loyola Chicago
7-22 Overall
2-9 Away
W-1 Streak
SLU Saint Louis
26-3 Overall
19-1 Home
W-1 Streak
LUC SLU
74.5 PPG 62.7
42.0% FG% 42.8%
30.7% 3PT% 34.2%
38.3 RPG 31.1
11.8 APG 13.3
7.3 SPG 7.1
14 TOPG 12.6
LUC Loyola Chicago
PlayerPPGRPGAPG
Blake Schilb 19.1 5.2 3.9
Paul McMillan 17.0 7.4 1.1
DaJuan Gouard 16.0 3.3 3.2
J.R. Blount 15.1 4.0 2.6
Majak Kou 12.9 4.0 1.3
SLU Saint Louis
PlayerPPGRPGAPG
Reggie Bryant 16.4 3.9 1.9
Kwamain Mitchell 15.9 3.0 3.0
Tommie Liddell 15.4 6.8 2.6
Kevin Lisch 14.9 3.6 3.5
Ian Vouyoukas 13.9 7.4 1.7
LUC Loyola Chicago
OppScore
H Richmond 69-66
A Saint Joseph's 61-75
A Fordham 59-62
H Saint Louis 59-86
A Davidson 64-84
SLU Saint Louis
OppScore
H Duquesne 91-76
A Dayton 62-77
H VCU 88-75
A Rhode Island 76-81
A Loyola Chicago 86-59
Book Spread ML Away ML Home O/U
DraftKings -22.5 2200 -8000 156.5
Fanatics -23 2500 -10000 155.5
BetMGM -22.5 2500 -10000 155.5
BetRivers -21.5 1400 -10000 155.5
Lines are subject to change. Odds pulled 1 month ago.
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